Weimin Gao, MD,
PhD
|
EDUCATION |
DEGREE |
YEAR |
FIELD |
|
|
MD |
1994 |
Preventive Medicine |
|
|
MPH |
1997 |
Toxicology and Occupational Medicine |
|
Graduate |
PhD |
2003 |
Environmental and Occupational Health Biostatistics |
|
The |
Postdoctoral fellow |
2004 |
Proteomics |
Research Interests:
Selected Publications:
Billam M, Mukhi S, Tang L, Gao W, Wang JS.
Toxic response indicators of microcystin-LR
in F344 rats following a single-dose treatment. Toxicon. 2008; in press
Tang L, Tang M, Xu
L, Luo H, Huang T, Yu J, Zhang L, Gao W,
Cox SB, Wang JS. Modulation of aflatoxin
biomarkers in human blood and urine by green tea polyphenols intervention.
Carcinogenesis. 2008;29(2):411-7.
Wang JS, Luo H,
Wang P, Tang L, Yu J, Huang T, Cox S, Gao
W. Validation of green tea polyphenol
biomarkers in a phase II human intervention trial. Food Chem Toxicol.
2008;46(1):232-40.
Liu Y, Gao W, Siegfried JM, Weissfeld JL, Luketich JD, Keohavong P. Promoter
methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung
tumors from smokers and never-smokers. BMC Cancer.
2007;7:74.
Sun G, Wang S, Hu
X, Su J, Huang T, Yu J, Tang L, Gao W, Wang JS.
Fumonisin B1 contamination of home-grown corn in high-risk
areas for esophageal and liver cancer in
Gao WM, Chadha MS, Berger RP, Omenn GS, Allen DL, Pisano M,
Adelson PD, Clark RS, Jenkins LW, Kochanek PM. A gel-based proteomic
comparison of human cerebrospinal fluid between inflicted and non-inflicted
pediatric traumatic brain injury. J Neurotrauma. 2007;24(1):43-53.
Omenn GS, Menon R, Adamski M,
Blackwell T, Haab BB, Gao W, States
DJ. The human plasma and serum proteome. In V. Thongbooonkerd (ed), Proteomics of
Human Body Fluids: Principles, Methods, and Applications. Humana Press,
Kochanek AR, Kline
AE, Gao WM, Chadha M, Lai Y, Clark RS, Dixon
CE, Jenkins LW. Gel-based hippocampal
proteomic analysis 2 weeks following traumatic brain injury to immature rats
using controlled cortical impact. Dev Neurosci.
2006;28(4-5):410-9.
Wang Z, Tang L,
Sun G, Tang Y, Xie Y, Wang S, Hu X, Gao
W, Cox SB, Wang JS. Etiological study of esophageal squamous
cell carcinoma in an endemic region: a population-based case control study in
Gao WM, Romkes M, Siegfried JM,
Luketich JD, Keohavong P. Polymorphisms in DNA repair genes XPD and
XRCC1 and p53 mutations in lung carcinomas of never-smokers. Mol
Carcinog. 2006;45(11):828-32.
Gao WM, Chadha MS, Kline
AE, Clark RS, Kochanek PM, Dixon CE, Jenkins LW. Immunohistochemical
analysis of histone H3 acetylation and methylation--evidence for altered
epigenetic signaling following traumatic brain injury in immature rats. Brain
Res. 2006;1070(1):31-4.
Luo H, Cox SB, Gao W, Yu J, Tang L, Wang JS. Metabolic Profiling in validation of plasma biomarkers for green tea polyphenols. Metabolomics. 2006;2(4):235-41.
Berger RP, Hymel K, Gao WM. The use of biomarkers after inflicted traumatic brain injury: insight into etiology, pathophysiology and biochemistry. Clinical Pediatric Emergency Medicine, 2006;7(3):186-93.
Gao WM, Kuick R, Orchekowski RP, Misek DE, Qiu J,
Greenberg AK, Rom WN, Brenner DE, Omenn GS, Haab BB, Hanash
SM. Distinctive serum protein profiles involving abundant proteins
in lung cancer patients based upon antibody microarray analysis. BMC Cancer. 2005;5:110.
Creighton CJ, Bromberg-White JL, Misek DE, Monsma DJ, Brichory F, Kuick R, Giordano TJ, Gao W, Omenn GS, Webb CP, Hanash SM. Analysis of tumor-host interactions by gene expression profiling of lung adenocarcinoma xenografts identifies genes involved in tumor formation. Mol Cancer Res. 2005;3(3):119-29.
Gao W, Keohavong P. Analysis of K-RAS and P53 mutations in sputum samples. Methods Mol Biol. 2005;291:217-33.
Keohavong P, Lan
Q, Gao WM, Zheng KC, Mady HH, Melhem MF, Mumford JL.
Detection of p53 and K-ras mutations in sputum of individuals exposed to smoky
coal emissions in
Gao WM, Romkes M, Siegfried JM,
Luketich JD, Keohavong P. No association between the XPD 312, 751,
or XRCC1 399 polymorphisms and K-ras gene mutation in smoking non-small-cell
lung cancer. Cancer Epidemiol Biomarkers Prev. 2004;13(4):673-5.
Keohavong P, Gao WM, Zheng KC, Mady
H, Lan Q, Melhem M, Mumford J. Detection
of K-ras and p53 mutations in sputum samples of lung cancer patients using
laser capture microdissection microscope and mutation
analysis. Anal Biochem. 2004;324(1):92-9.
Keohavong P, Gao WM, Mady HH, Kanbour-Shakir A, Melhem MF. Analysis of p53 mutations in cells taken from paraffin-embedded tissue sections of ductal carcinoma in situ and atypical ductal hyperplasia of the breast. Cancer Lett. 2004;212(1):121-30.
Gao WM, Romkes M, Day RD,
Siegfried JM, Luketich JD, Mady HH, Melhem MF, Keohavong P. Association of the DNA
repair gene XPD Asp312Asn polymorphism with p53 gene mutations in
tobacco-related non-small cell lung cancer. Carcinogenesis.
2003;24(10):1671-6.
Keohavong P, Lan
Q, Gao WM, DeMarini
DM, Mass MJ, Li XM, Roop BC, Weissfeld
J, Tian D, Mumford JL. K-ras mutations in lung carcinomas from
nonsmoking women exposed to unvented coal smoke in
Zhang LF, Gao WM, Gealy
R, Weissfeld J, Elder E, Whiteside TL, Keohavong P.
Comparison of K-ras gene mutations in tumour and
sputum DNA of patients with lung cancer. Biomarkers.
2003;8(2):156-61.
Gao WM, Mady HH, Yu GY, Siegfried
JM, Luketich JD, Melhem MF, Keohavong P. Comparison
of p53 mutations between adenocarcinoma and squamous cell carcinoma of the
lung: unique spectra involving G to A transitions and G to T transversions in both histologic
types. Lung Cancer. 2003;40(2):141-50.
Gao WM, Lu HM, Dong JC, Zhang W, Zhou XY, Jenkins LW, Dixon CE. Postnatal growth, neurobehavioral and neurophysiologic changes of prenatal low-dose beta-radiation from tritiated water in mice. Neurotoxicol Teratol. 2002;24(2):247-54.
Keohavong P, Mady HH, Gao WM, Siegfried JM, Luketich JD, Melhem MF. Topographic analysis of K- ras mutations in histologically normal lung tissues and tumours of lung cancer patients. Br J Cancer. 2001;85(2):235-41.
DeMarini DM, Landi S, Tian D, Hanley NM, Li X, Hu F, Roop BC, Mass MJ, Keohavong P, Gao W, Olivier M, Hainaut P, Mumford JL. Lung tumor KRAS and TP53 mutations in nonsmokers reflect exposure to PAH-rich coal combustion emissions. Cancer Res. 2001;61(18):6679-81.
Gao WM, Wang B, Zhou XY. Effects of prenatal
low-dose beta radiation from tritiated water on
learning and memory in rats and their possible mechanisms. Radiat
Res. 1999;152(3):265-72.
Wang B, Takeda H, Gao WM, Zhou XY, Odaka T, Ohyama H, Yamada T, Hayata I. Induction of apoptosis by beta radiation from tritium compounds in mouse embryonic brain cells. Health Phys. 1999;77(1):16-23.