| Principles
of Toxicology I |
| ENTX
4325 and 6325 |
| Fall
2007 |
| TOPIC
SCHEDULE and NOTES |
| T/TH
8:00 - 9:20 AM |
| Room:
TIEHH Auditorium |
| 3
Credit hours |
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Date |
|
Topic |
|
Reading* |
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Lecturer |
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Aug |
|
28 |
Introduction,
Scope and Chemical Types |
Handouts |
|
Hooper |
|
Aug |
|
30 |
History
of Toxicology |
1 |
|
Hooper |
|
Sept |
|
4 |
Basic
Principles: Dose-Response Relationships, |
2 |
|
Hooper |
| H-1a |
Sept |
|
6 |
Testing Methods and Quantitation |
2 |
|
Hooper |
|
Sept |
|
11 |
Reactive
Metabolites / Chemical Injury and |
3 |
|
Hooper |
|
Sept |
|
13 |
Protection Mechanisms |
3 |
|
Hooper |
|
Sept |
|
18 |
Absorption |
5 |
|
Hooper |
|
Sept |
|
20 |
Distribution
|
5 |
|
Hooper |
|
Sept |
|
25 |
Excretion |
|
5 |
|
Hooper |
|
Sept |
|
27 |
|
4 |
|
Hooper |
|
Oct |
|
2 |
**
EXAM I |
- |
|
- |
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Oct |
|
4 |
Metabolism
of Toxicants - Phase I - part 1 HW-I |
6 |
|
Hooper |
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Oct |
|
9 |
Metabolism
of Toxicants - Phase I - part 2 |
6 |
|
Hooper |
| H-1b |
Oct |
|
11 |
Metabolism
of Toxicants - Phase I - part 3 |
6 |
|
Hooper |
|
Oct |
|
16 |
Conjugation
and Elimination - Phase II - Part 1 |
6 |
|
Hooper |
|
Oct |
|
18 |
Conjugation
and Elimination - Phase II - Part 2 |
6 |
|
Hooper |
|
Oct |
|
23 |
Case-Studies
of Metab A B C HW
Info |
Handouts |
|
Hooper |
|
Oct |
|
25 |
Physiological
Factors |
H&S 7 |
|
Hooper |
|
Oct |
|
30 |
Nutritional
Factors Nucleotides |
H&S 11 |
|
Hooper |
|
Nov |
|
1 |
**
EXAM II |
- |
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- |
|
Nov |
|
6 |
Hepatotoxicology
I |
13 |
|
Hooper |
|
Nov |
|
8 |
Hepatotoxicology
II |
13 |
|
Hooper |
| |
Nov |
|
13 |
Molecular
and Population Epidemiology I |
H&S 17 and |
|
Wang |
|
Nov |
|
15 |
Molecular
and Population Epidemiology II |
handouts |
|
Wang |
| H2 |
Nov |
|
20 |
Renal
Toxicology I |
14 |
|
Hooper |
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Nov |
|
22 |
Thanksgiving
Break |
- |
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- |
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Nov |
|
27 |
Renal
Toxicology II |
14 |
|
Hooper |
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Nov |
|
29 |
Neurotoxicology
I |
16 |
|
Hooper |
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Dec |
|
4 |
Neurotoxicology
II |
16 |
|
Hooper |
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Dec |
|
6 |
Risk
Assessment |
16 |
|
Hooper |
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Dec |
|
8 |
Saturday,
7:30am-9:30am - Final Exam - COMPREHENSIVE |
|
Hooper |
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| *
Numbers refer to chapters in Casarett and Doull's Toxicology.
H&S = Hodgeson and Smart |
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"H"
Indicates homework due this day
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