CURRICULUM VITAE
(Jia-Sheng Wang)
CURRENT POSITION:
Professor
Department of Environmental Toxicology
College of Arts & Sciences
Texas Tech University &
Full Member and Leader
Division of Human Health Sciences
The Institute of Environmental and Human Health
Texas Tech University/Texas Tech University Health Science Center
CONTACT INFORMATION:
Mail Stop 1163
Department of Environmental Toxicology &
The Institute of Environmental and Human Health
Texas Tech University
Room 101L, Building 555
Reese Technology Center
Lubbock, TX 79409-1163
Telephone: (806)885-0320 (Office)
(806)885-0283 (Laboratory)
Fax: (806)885-2132
E-mail: js.wang@ttu.edu or j.s.wang@tiehh.ttu.edu
1302 Mobile Avenue
Lubbock, Texas 79416
Telephone/Fax: (806) 795-0365
EDUCATION AND TRAINING:
National Institute of Environmental Health Sciences Post-doctoral Fellow, Molecular Epidemiology, Department of Environmental Health Science, School of Hygiene and Public Health, Johns Hopkins University (1994-1995)
Ph.D, Pathology, 1994, Boston University School of Medicine, Boston, Massachusetts.
Doctor Degree of Medicine, Toxicology, 1982, Shanghai First Medical College, Shanghai, PRC.
Internship, Shanghai Mei Shan Hospital, 1977, Shanghai, PRC.
M.B., Preventive Medicine, 1978, Shanghai First Medical College, Shanghai, PRC.
PROFESSIONAL EXPERIENCE:
Professor of Molecular Toxicology, Department of Environmental Toxicology, College of Science and Arts, Texas Tech University (2006-)
Visiting Professor, Southern Yangtze University, Wuxi, P.R. China (June 2004- )
Visiting Professor, Guangxi Medical University, Nanning, PR. China (September 2001- )
Associate Professor of Molecular Toxicology, Department of Environmental Toxicology, College of Science and Arts, Texas Tech University (May 2000-; tenured in 2002)
Visiting Professor, Shanghai Medical University School of Public Health, Shanghai, PR China (1999- )
Research Assistant Professor, Division of Toxicological Sciences, Department of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University (1997- )
Visiting Professor, Southeast University School of Public Health, Nanjing, P. R. China (1996- )
Research Associate, Division of Toxicological Sciences, Department of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University
(1994-1996)
Research Affiliate, Division of Toxicology, Massachusetts Institute of Technology (1992-1993)
Ph.D Candidate and Research Assistant, Oncology and Hematology Section, Department of Pathology and Laboratory Medicine, Boston University School of Medicine (1990-1993)
Visiting Scientist, Division of Toxicology, Department of Applied Biological Science, and Center for Environmental Health Sciences, Massachusetts Institute of Technology (1986-1991)
Assistant Professor, Division of Toxicology and Division of Nutrition and Food Hygiene, Department of Preventive Medicine, Nanjing Railway Medical College (1982-1985)
Head, Laboratory of Toxicology, Department of Preventive Medicine, Nanjing Railway Medical College (1983-1986)
Assistant Dean for Research, Nanjing Railway Medical College (1984-1985)
Associate Director for Student Affairs, Nanjing Railway Medical College (1983-1984)
Acting Director, Division of Nutrition and Food Hygiene, Department of Preventive Medicine, Nanjing Railway Medical College (1982)
Teaching and Research Assistant, Food Toxicology Program, Department of Nutrition and Food Hygiene, Shanghai First Medical College (1978-1981)
PROFESSIONAL ACTIVITIES:
Society Full Membership:
American Association for Cancer Research
American Association for the Advancement of Science
American Society of Toxicology
American Society for Cell Biology
American Society of Microbiology
American Society of Nutrition
American Society of Preventive Oncology
The Society of Environmental Toxicology and Chemistry
The Society of Metabolomics
Professional Committees:
President-elect, American Association of Chinese in Toxicology (2006-)
Vice President-elect, Food Safety Specialty Section, Society of Toxicology (2006-)
Board Member, American Association of Chinese in Toxicology (2005-)
Secretary, American Chinese Society of Toxicology (2003-2005 )
General Secretary, Advisory Committee for Food Hygiene and Safety in Jiangsu Province (1984-1986)
Co-chair of subcommittee of Nutrition and Food Safety, Committee for Development of Food Science and Technology, Jiangsu Province (1984-1986)
Consultations:
Technical consultant for Mycotoxin Detection in ADA Technologies, Inc., Littleton, CO (2005- )
Technical Consultant for Mycotoxin Detection in VICAM, Watertown, MA (1997-1999)
Seafood Safety and Contaminations for Baltimore Sun (September 1995, January 1998)
EDITORIAL ACTIVITIES
Peer Review Activities:
Serve as peer reviewer for “Carcinogenesis”,“ Cancer Research”, “Cancer Epidemiology, Biomarkers and Prevention”, “International Journal of Cancer”, “Toxicology and Applied Pharmacology”, “Journal of Biochemical Pharmacology”, and “Journal of the National Cancer Institute”, “Journal of Nutrition”, “Journal of Laboratory Investigation”, “Environmental Toxicology and Chemistry”, and “Food Additives and Contaminants”, “Cancer Letters” from 1990 to present.
HONORS AND AWARDS
Excellence Teaching Award in Basic Medical Sciences, Awarded by Nanjing Railway Medical College (1983-1985)
Distinguish Research Award for Food Safety, Awarded by Jiangsu Province (1985)
National Research Award in Trichothecene Mycotoxicosis Awarded by State Scientific Commission of PRC (1987)
Outstanding Faculty, TIEHH (2006)
PUBLICATIONS
Peer Reviewed Journal Articles:
Wang, J.-S., Luo, H., Wang, P. Tang, L., Yu, J., Huang, T., Cox, S. B., Gao, W. (2007). Validation Validation of Green Tea Polyphenol Biomarkers in a Phase II Human Intervention Trial. Food Chem Toxicol. In press
Wang, P., Afriyie-Gyawu, E., Tang, Y., Johnson,N. M., Xu, L., Tang, L., Huebner, H. J., Ankrah, N.-A., Ofori-Adjei, D., Ellis, W., Jolly, P. E., Williams, J. H., Wang, J.-S., Phillips, T. D. (2007). NovaSil clay intervention in Ghanaians at high risk for aflatoxicosis: II. Reduction in biomarkers of aflatoxin exposure in blood and urine, Food Additives & Contaminants, In press.
Phillips, T. D., Afriyie-Gyawu, E., Williams, J., Huebner, H., N-A. Ankrah, N-A., Ofori-Adjei, D., Jolly, P., Johnson, N., Taylor, J., Marroquin-Cardona, A., Xu, L., Tang, L., Wang, J.-S. (2007). REDUCING HUMAN EXPOSURE TO AFLATOXIN THROUGH USE OF CLAY. Food Additives & Contaminants, In press.
Cai, Q., Tang, L. and Wang, J.-S. (2007). Validation of fumonisin biomarkers in F344 rats. Toxicol Appl. Pharmacol. In press.
Afriyie-Gyawu, E., Ankrah, N.-A., Huebner, H. J., Ofosuhene, M., Kumi, J., Johnson, N. M., Tang, L., Xu, L., Jolly, P.E., Ellis, W. O., Ofori-Adjei, D., Williams, J. H., Wang, J.-S. & Phillips, T. D. (2007). NovaSil clay intervention in Ghanaians at high risk for aflatoxicosis. I. Study design and clinical outcomes. Food Additives & Contaminants, In press
Tang, L., Guan H., Ding, X. and Wang, J.-S. (2007). Modulation of aflatoxin toxicity and biomarkers by lycopene in F-344 rats. Toxicol Appl. Pharmacol. 219:10-17.
Sun, G., Wang, S., Hu, X., Su, J., Huang, T., Yu, J., Tang, L., Gao, W. and Wang, J.-S. (2007). Fumonisin B1 contamination of home-grown corn in high-risk areas of esophageal and liver cancers in China. Food Additives & Contam. 24(2):181-185.
Dash, B., Afriyie-Gyawu, E, Huebner, H. J., Porter, W., Wang, J.-S, Jolly, P. E., Phillips, T. D. (2007). Determinants of the variability of aflatoxin-albumin adduct levels in Ghanaians. J Toxicol. Environ. Health Part A 70:58-66.
Luo, H., Cox, SB., Gao, W.-M., Yu, J., Tang, L. and Wang, J.-S. (2006). Metabolic Profiling in Validation of Plasma Biomarkers for Green Tea Polyphenols. Metabolomics, 2(4):235-241.
Wang, Z., Tang, L., Sun, G., Tang, Y., Xie, Y., Wang, S., Hu, X., Gao, W., Cox, S. B. and Wang J.-S. (2006). Etiological study of esophageal squamous cell carcinoma in an endemic region: a population-based case control study in Huaian, China. BMC Cancer 2006, 6:287 doi:10.1186/1471-2407-6-287
Pan XP, Zhang BH, Tian K, Jones LE, Liu J, Anderson TA, Wang J.-S., Cobb GP (2006). Liquid chromatography-electrospray ionization-tandem mass spectrometry analysis of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX). Rapid Communications in Mass Spectrometry 20:2222-2226.
Egner, PA, Groopman, JD., Wang, J.-S., Kensler, TW., and Friesen, MD (2006). Quantification of aflatoxin B1-N7-guanine in human urine by HPLC-Isotope-Dilution Tandem Mass Spectrometry. Chem. Res. Toxicol. 18:1191-1195.
Luo, H., Tang, L., Billam, M., Tang, M., Huang, T., Yu, J., Wei, Z., Liang, Y., Wang, K., Zhang, Z., Zhang, L., and Wang, J.-S. (2006). Phase IIa chemoprevention trial of green tea polyphenols in high-risk population of liver cancer: II. Modulation of urinary excretion of green tea polyphenols and 8-hydroxydeoxyguanosine. Carcinogenesis 27:262-268.
Billam, M., Tang, L., Cai, Q., Mukhi, S., Guan, H., Wang, P., Wang, Z. and Wang, J.-S. (2006). Seasonal Variations in the Concentration of Microcystin-LR Contamination in Lakes of West Texas. Environ. Toxicol. Chem. 25(2):356-366.
McKean, C., Tang, L., Billam, M., Tang, M., Theodorakis, C. W., Kendall, R. J. and Wang, J.-S (2006). Comparative acute and combinative toxicity of aflatoxin B1 and T-2 toxin in animals and immortilized human cell lines. J. Appl Toxicol. 26(2):139-147.
McKean, C., Tang, L., Tang, M., Billam, M., Wang, Z.,Theodorakis, C. W., Kendall, R. J. and Wang, J.-S (2006). Comparative acute and combinative toxicity of aflatoxin B1 and fumonisin B1 in animals and human cell lines. Food Chem. Toxicol. 44(6):868-876.
Dash, B., Afriyie-Gyawu, E, Huebner, H. J., Porter, W., Wang, J.-S, Jolly, P. E., Phillips, T. D. (2006). Noninvasive identification of inter-individual variation in xenobiotic metabolizing enzymes: implications for cancer epidemiology and biomarker studies. J Toxicol. Environ. Health A 69(13):1203-1216.
He, X-Y., Tang, L., Wang, S-L., Cai, Q., Wang, J.-S. and Hong, J-Y. (2006). Efficient activation of aflatoxin B1 by cytochrome P450 2A13, an enzyme predominantly expressed in human respiratory tract. International J. Cancer, 118(11):2665-2671.
Jolly, P., Jiang, Y., Ellis, W., Awuah, R., Nnedu, O., Phillips, T., Wang, J.-S., Tang, L., Afriyie-Gyawu, E., Person, S., Williams, T. and Jolly, C. (2006). Determinants of aflatoxin levels in Ghanaians: sociodemographic factors, knowledge of aflatoxin and food handling and consumption practices. International J. Hyg. & Environ. Health 209:345-358.
Liu, F., Wang, J.-S., and Theodorakis, C.W. (2006). Genotoxicity and oxidative stress caused by sodium arsenate and sodium perchlorate in zebrafish Danio rerio. Environ Sci. Technol. 40:3429-3436.
Tang, L., Jin, T., Zheng, X. and Wang, J.-S. (2005). Lycopene inhibits the growth of human androgen-independent prostate cancer cells in vitro and in BALB/c nude mice. J. Nutr. 135(2): 287-290.
Afriyie-Gyawu, E., Mackie, J., Dash, B., Wiles, M., Taylor, J., Huebner, H., Tang, L., Guan, H., Wang, J.-S. and Phillips, T. D. (2005). Long-term toxicological evaluation of NovaSil clay in the diet of Sprague-Dawley rats. Food Add & Contam. 22 (3): 259-269
Wang, J.-S., Luo, H., Billam, M., Wang, Z., Guan, H., Tang, L., Goldston, T., Afriyie-Gyawu, E., Lovett, C., Griswold, J., Brattin, B., Huebner, H. J. and Phillips, T. D. (2005). Short-term safety evaluation of NovaSil in humans. Food Add. & Contam. 22 (3): 270-279.
Wang, J.-S and Tang, L. (2004). Aflatoxin exposure and human liver cancer. J. of Toxicol, 23:249-271.
Tang, L., Tang, M., He, X., Busby, W. F., and Wang, J.-S. (2004). Tumorigenicity of airborne complex mixtures. J. Toxicol. Pharmacol. 18:134-140.
Sun, G., Xiong, C., Zhang, Y., Wang, S., Xie, Y. Wang, H., Shi, N. and Wang, J.-S. (2004). Comparison of contents of trace elements in wheat samples from the control and endemic Kashin-Beck disease areas. Trace Element & Health, 21:23-26.
Wu, Y., Lu, P., Wang, J.-S., Wang, J., Wan, S., Kensler T. W., Groopman, J. D. and Qian, G.-S (2003). Correlation between the genetic polymorphism of EPHX and susceptibility to hepatocellular carcinoma, Tumor, 23:287-289.
Sun, G.-J., Qian, G.-S., Jin, X.-P., Chen, J.-G., He, X., Wang S.-K., Jiang, Z-K., and Wang, J.-S. (2002). Assessment of aflatoxin exposure in residents with high incidence of liver cancer. J. Southeast University (Med.Sci.) 21:118-122.
Wang, J.-S., Abubaker, S., He, X., Sun, G., Strickland, PT., and Groopman, JD. (2001). Development of aflatoxin B1-lysine adduct monoclonal antibody for human exposure studies. Appl. Environ. Microbiol. 67:2712-2717.
Wang, J.-S., Huang, T., Su, JJ., Liang, F., Wei, Z., Liang, Y., Luo, H., Kuang, S-Y., Qian, G-S., Sun, G., He, X., Kensler, TW., and Groopman, JD. (2001). Hepatocellular carcinoma and aflatoxin exposure in Zhuqing Village, Fusui County, People's Republic of China. Cancer Epidemiol. Biomarker & Prev. 10:143-146.
Sun G, Qian, G-S, He X, Jing X-P, Wang J-S (2001). Measurement of serum aflatoxin-albumin adducts in high-risk populations of primary liver cancer. Health Res, 30:207-210.
Li, Y., Su, J., Qin, L., Egner, PA., Wang, J-S., Groopman, JD., Kensler, TW., and Roebuck, BD. (2000). reduction of aflatoxin B1 adduct biomarkers by oltipraz in the tree shrew (Tupaia belangeri chinensis). Cancer Lett. 154:79-83.
Sun, G., He, X., Qian, G.-S., Jing, X.-P., Wang, J.-S. (2000). The detection of aflatoxin metabolites in human urine using high-pressure liquid chromatography. J. Health Toxicol. 14:250-252.
Wang, S.S., O’Neill, J. P. Qian, G.-S., Zhu Y-R., Wang, J-B., Armenian, H., Zarba, A., Wang, J.-S., Kensler, T.W., Cariello, N. F., Groopman, J. D., and Swenberg, J. A. (1999). Elevated HPRT mutation frequencies in aflatoxin-exposed residents of Daxin, Qidong county, People’s Republic of China. Carcinogenesis 20 (11):2181-2184
Wang, J.-S, He, X., Mulder, P. P. J., Boere, B. B., Cornelisse, J., Lugtenburg, J. and Busby, W. F. Jr. (1999). Comparative tumorigenicity of the cyclopenta-fused polynuclear aromatic hydrocarbons, aceanthrylene, dihydroaceanthrylene, and acephenanthrylene in preweanling CD-1 and BLU:Ha mouse bioassays. Carcinogenesis 20:1137-1141.
Rashid, A., Wang, J.-S., Qian, G.-S., Lu, B.-X., Hamilton, S. R. and Groopman, J. D. (1999) Genetic alterations in hepatocellular carcinomas: association between loss of chromosome 4q and p53 gene mutations. Brit. J. Cancer 80:59-66.
Wang, J.-S, Shen, X., He, X., Zhou, Y.-R., Zhang, B.-C., Wang, J.-B., Qian, G.-S., Kuang, S.-Y., Zarba, A., Egner, P. A., Jacobson, L. P., Munoz, A., Helzlsouer, K. J., Groopman, J. D. and Kensler, T. W. (1999) Protective alterations in phase 1 & 2 metabolism of aflatoxin B1 by Oltipraz in residents of Qidong, People’s Republic of China. J. Natl Cancer Inst. 91:347-354.
Wang, J.-S and Groopman, J. D. (1999) DNA damage by mycotoxins, Mutation Res. 424:167-181.
Kensler, T. W., He, X., Otieno, M., Egner, P. A., Jacobson, L. P., Chen, B., Wang, J.-S., Zhu, Y.-R., Zhang, B.-C., Wang, J.-B., Wu. Y., Zhang Q.-N., Qian, G.-S., Kuang, S.-Y., Fang, X., Li, Y-F., Yu, L-Y., Prochaska, H. J., Davidson, N. E., Gordon, G. B., Gorman, M. B., Zarba, A., Enger, C., Munoz, A., Helzlsouer, K. J., and Groopman, J.D. (1998). Oltipraz chemoprevention trial in Qidong, People’s Republic of China: modulation of serum aflatoxin albumin adduct biomarkers. Cancer Epidemiol. Biomarkers & Prev. 7:127-134.
Zhang, B.-C., Zhu, Y.-R., Wang, J.-B., Wu, Y., Zhang, Q.-N., Qian, G.-S., Kuang, S.-Y., Li, Y.-F., Fang, X., Yu, L.-Y., De Flora, S., Jacobson, L. P., Zarba, A., Egner, P. A., He, X., Wang, J.-S., Chen, B., Enger, C. L., Davidson, N. E., Gordon, G. B., Gorman, M. B., Prochaska, H. J., Groopman, J. D., Munoz, A., Helzlsouer, K. J. And Kensler, T. W. (1997). Oltipraz Chemoprevention Trial in Qidong, Jiangsu Province, People’s Republic of China. J. Cell. Biochem. Suppl. 28/29: 166-173.
Wang, J.-S., Couburn, J., Tauber, A. I. and Zaner, K. S. (1997).role of gelsolin in actin depolymerization in adherent human neutrophils, Molecul Biol Cell. 8:121-128.
Li, Y., Yokoi, T., Katsuki, M., Wang, J.-S., Groopman, J. D., and Kamataki, T. (1997). In vivo activation of aflatoxin B1 in C57BL/6N mice carrying a human fetus-specific CYP3A7 gene, Cancer Res. 57:641-645.
Mace, K., Aguilar, F., Wang, J-S., Vautravers, P., Gomez-Lechon, M., Gonzalez, F. J., Groopman, J., Harris, C. C. and Pfeifer, A. M. A. (1997). Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450-expressing human liver cell lines. Carcinogenesis 18:1291-1297.
Wang, J.-S., Busby, W. F. Jr., and Wogan, G. N. (1996). Comparative percutaneous absorption and tissue distribution of [3H]diacetoxyscirpenol (anguidine) in rats and mice,
Toxicol. Appl. Pharmacol. 140:264-273.
Wang, J.-S and Busby, W. F. Jr. (1996). Bacterial and human cell mutagenicity and mouse lung tumorigenicity of the oxygenated PAH, phenalenone, Fund. Appl. Toxicol. 33:212-219.
Wang, J.-S., Qian, G.-S., Zarba, A., He, X., Zhu, Y.-R., Zhang, B.-C., Jacobson, L., Gange, S. J., Munoz, A., Kensler, T. W., and Groopman, J. D. (1996). Temporal patterns of aflatoxin-albumin adducts in hepatitis B surface antigen positive and negative residents of Daxin, Qidong County, People’s Republic of China. Cancer Epidemiol. Biomarker Prev. 5 (4):253-261
Gange, S. J., Munoz, A., Wang, J.-S., and Groopman, J. D. (1996). Variability of molecular biomarker measurements from nonlinear calibration curves.Cancer Epidemiol. Biomarker & Prev. 5(1),57-61.
Soini, Y., Chia, C. S., Bennett, W. P., Groopman, J. D., Wang, J.-S., DeBenedetti, V. M. G., Cawley, H., Welsh, J. A., Hansen, C., Bergasa, N. V., Jones, E. A., DiBisceglie, A. M., Trivers, G. E., Sandoval, C. A., Calderon, I. E., Munoz-Espinosa, L. E. and Harris, C. C. (1996). An aflatoxin-associated, mutational hotspot in the p53 tumor suppressor gene occurs in hepatocellular carcinomas from Mexico Carcinogenesis 17 (5):1007-1012.
Wang, J.-S., Busby, W. F. Jr. and Wogan, G. N. (1995). Formation and persistence of DNA adducts in organs of CD-1 mice treated with a tumorigenic dose of fluoranthene. Carcinogenesis, 16(11):2609-2616
Wang, J.-S., Busby, W. F. Jr. and Wogan, G. N. (1995). Tissue distribution of DNA adducts in preweanling BLU:Ha mice treated with a tumorigenic dose of fluoranthene. Cancer Lett. 92:9-19.
Sastry, R., Wang, J.-S., Brown, D. C., Ezekowitz, R. A. B., Tauber, A. I., and Sastry, K. N. (1995). Characterization of murine mannose-binding protein genes Mbl1 and Mbl2 reveals features common to other collectin-genes, Mammal. Genome 6:103-110.
Wang, J.-S. and Busby, W. F. Jr. (1993). Induction of lung and liver tumors by fluoranthene in a preweanling CD-1 mouse bioassay, Carcinogenesis 14:1871-1874.
Wang, J.-S., Pavlotsky, N., Tauber, A. I. and Zaner, K. S. (1993). Assembly dynamics of actin in adherent human neutrophils, Cell Motil. Cytoskeleton 26:340-348.
Ginis, I., Zaner, K. S., Wang, J.-S., Pavlotsky, N. and Tauber, A. I. (1992). Comparison of actin changes and calcium metabolism in plastic- and fibronectin-adherent human neutrophils, J. Immunol. 149:1388-1394.
Wang, J.-S., Busby, W. F. Jr. and Wogan, G. N. (1990). Comparative tissue distribution and excretion of orally administered [3H]-diacetoxyscirpenol (anguidine) in rats and mice, Toxicol. Appl. Pharmacol. 103:430-440.
Busby, W. F. Jr., Wang, J.-S., Stevens, E. K., Padykula, R. E., Aleksejczyk, R. A. and Berchtold, G. A. (1990). Lung tumorigenicity of benzene oxide, benzene dihydrodiols and benzene diolepoxides in the BLU:Ha newborn mouse assay, Carcinogenesis 9:1473-1478.
Xu, D., and Wang, J.-S. (1988). Advances in research on trichothecenes T-2, DON and NIV. Adv. Physiol. Sci.19:103-109.
Wang, J.-S. and Sun, Q. (1988). Mutagenicity studies in vivo of zearalenone, a Fusarium mycotoxin, in mice, Acta Mycologica Sinica 7 (1):59-64.
Wang, J.-S., Zhang, Z. Y. and Zhu, X. Y. (1987). Toxicological studies (acute and accumulative toxicity, mutagenicity and cytogenetic evaluation) of Extract from Fucorose, Chinese J. Rail. Med. 15(1):52-56.
Tan, W. B., Wang, J.-S., Shan, X. N., Zhang, Z. Y. and Zhu, X. Y. (1986). Evaluation of nutritional status of preschool children from railway workers, Chinese J. Rail. Med. 14 (4):233-236
Wang, J.-S. and Xu, D. D. (1986). Mutagenic and teratogenic studies of mycotoxins extracted from scabby wheat, Acta Mycologica Sinica 5(1):52-62.
Wang, J.-S. and Zhu X. Y. (1985). Investigation of aflatoxin M1 contamination in milk and milk powder, Chinese J. Rail. Med. 13 (6):354-357.
Wang, J.-S. and Jiang, Z. K. (1984). Assessment of inorganic and organic arsenic accumulation in various seafood, Chinese J. Rail. Med. 12 (5):289-292.
Tang, W. L., Jiang, Z. K., Huang, W. Q., Zhang, Z. Y., Zhu, X. Y., and Wang, J.-S. (1983). Toxicological studies of NE-109, a growth regulator of plant, in rats and mice, Chinese J. Prevent. Med. 25 (6):2020-2025.
Wang, J.-S. and Xu, D. D. (1982). Absorption, tissue distribution and metabolism of Fusarium mycotoxins, Chinese J. Public Health, 6:333-341.
Wang, J.-S. and Xu, D. D. (1982) Carcinogenicity, mutagenicity and teratogenicity studies of Fusarium mycotoxins from scabby wheat, Chinese J. Public Health, 2:75-80
Dissertations:
Wang, J.-S. (1981). Toxicological studies of Fusarium mycotoxins from scabby wheat causing human toxicosis. Dissertation for Post-Graduate Study, Shanghai First Medical College.
Wang, J.-S. (1994) Regulatory mechanisms of actin depolymerization in adherent human neutrophils, Ph.D Dissertation, Boston University School of Medicine.
Published Reviews and Book Chapters:
Wang, J.-S., Huang, T., Yu, J., Tang, L., Luo, H., Billam, M., Wei, Z., Liang, Y., Li, Y., Wang, K., Shi, J., Cui, Y., Zhang, Z-Q., Zhang, L., Sun, S., and Martin, C. Phase IIa chemoprevention trial of green tea polyphenols in high-risk population of liver cancer: I. Design, clinical outcome, and baseline biomarker data. In Cancer Prevention, Nova Sci. Publishers, 2006, in press.
Wang, J.-S. and Tang, L. Epidemiology of aflatoxin exposure and liver cancer, In: Aflatoxin and Food Safety, Hamed K. Abbas (ed), CRC Press, Taylor & Francis, Boca Raton, FL, 2005, pp195-211.
Groopman, J. D., Jackson , P. E., Wang, J.-S., and Kensler, T.W. (2002). Molecular Biomarkers for Liver Cancer, Comprehensive Toxicology, 23: 345-363.
Wang, J.-S, Links, J. M. And Groopman, J.D. (2002). Molecular epidemiology and Human risk monitoring.In: Molecular Drug Metabolism and Toxicology, OCIA International Press, London, pp147-166.
Wang, J.-S., Links, J. M. and Groopman, J. D.(2001). Molecular epidemiology and biomarkers, In: Choy WN Ed, Genetic Toxicology and Cancer Risk Assessment, Marcel Dekker, New York, pp269-296.
Wang, J.-S. and Groopman, J. D.(2000).Hepatic disorders. In Levy, BS and Wegman DH, Eds. Occupational Health:Recognizing and Preventing Work-Related disease, Lippincott Williams & Wilkins, Philadelphia, pp631-639.
Wang, J.-S, Kensler, T. W. and Groopman, J. D. (1998) Toxicants in Food: Fungal Contaminants.In:Ioannides C Ed. Current Toxicology Series: Nutrition and Chemical Toxicity, John Wiley & Sons, Chichester, pp29-57
Wang, J.-S. and Groopman, J. D. (1998). Biomarkers for carcinogen exposure: tumor initiation. In Walace, KB and Puga, A (eds). Molecular Biology in Toxicology, Taylor & Francis, Washington, DC, pp145-166.
Wang, J.-S. and Groopman, J. D. (1998).Toxic liver disorders. In Rom, WR ed. Environmental and Occupational Medicine, 3rd Edition, Lippincot-Raven Publishers, Philadelphia, pp831-841.
Groopman, J. D., Scholl, P., and Wang, J.-S. (1996). Epidemiology of human aflatoxin exposure and their relationship to liver cancer. In Walker, C et al (eds) Genetics and Cancer Susceptibility: implications for risk assessment, Wiley-Liss, New York, pp.211-222.
Groopman, J. D., Wang, J.-S., and Scholl, P. (1996). Molecular biomarkers for aflatoxins: From adducts to gene mutations to human liver cancer. Canad. J. Physiol. Pharmacol. 74:203-209.
Groopman, J. D., Wang, J.-S., Scholl, P., and Kensler, T. W. (1995) Induction of aflatoxin carcinogenesis and mutational spectra. Proc. AACR 36:657-658
Xu, D. D. and Wang, J.-S. (1987). Research advances on trichothecene mycotoxins from scabby wheat, Chinese J. Fd. Hygiene 5 (1):17-25.
Wang, J.-S. (1982). Genetic Toxicology, Chinese J. Public Health, 6:2861-2876
Published Abstracts:
Wang, Z., Tang, Y., Sun, G., Xie, Y.,
Wang, S., Hu, X., Tang, L., Wang, J.-S. (2006).
Genetic polymorphisms of DNA repair enzyme
XRCC1 and alcohol metabolizing enzymes ALDH2, ADH2, and ADH3 on susceptibility
to esophageal cancer in Huaian, China, Porc AACR, In press
Yu, J., Huang, T., Zhang, L., Wei, Z., Liang, R., Li, Y., Wang, K., Shi, J., Luo, H., Tang, L., Tang, Y., Zhang, Z-Q., Wang, J.-S. (2006). Chemoprevention Trial of Green Tea Polyphenols in High-Risk Population of Liver Cancer in Southern Guangxi, China, Proc AACR, In press.
Liu, F, Wang, J.-S., Hooper, M.J., and Theodorakis, CW. (2006) Evaluation on toxicity of sodium perchlorate and sodium arsenate using zebrafish Danio Rerio as a model: genotoxicity and oxidative stress perspective. Toxicologist, 90:1191.
Wang, Z., Tang, Y., Luo, H., Sun, G., Xie, Y., Wang, S., Hu, X., Tang, L., Wang, J.-S. (2006). Role of Oxidative DNA Damage in Human Esophageal Carcinogenesis, Toxicologist, 90:957.
Billam, M., Cai, Q., Mukhi, S., Tang, L., Kendall, R. J., Wang, J.-S. (2006). Molecular Targets and Toxic Effects of Microcystin-LR in F344 Rats, Toxicologist, 90:176.
Billam, M., Cai, Q., Tang, L., Wang, P., Mukhi, S., Wang, Z., Luo, H., Guan, H. and Wang, J.-S. (2005). Temporal Patterns of Microcystin-LR Contamination in Lakes of West Texas. Toxiclogist, 84:1595.
Cai, Q., Guan, H., Tang, L., Luo, H., Billam, M., Wang, Z., Tang, Y. and Wang, J.-S. (2005). Validation of Fumonisin Biomarkers in F344 rats. Toxicologist, 84:1308.
Wang, J.-S, Goldston, T., Luo, H., Billam, B., Wang, Z., Guan, H., Tang, L., Afriyie-Gyawu, E., Lovett, C., Griswold, J., Brattin, B., Huebner, H. J. and Phillips, T.D. (2005). Short-term safety evaluation of NovaSil in humans. Toxicologist, 84:1309.
Afriyie-Gyawu, E., Mackie, J., Dash, B., Wiles, M. C., Taylor, J., Huebner, H. J., Guan, H., Tang, L., Wang, J,-S. and Phillips, T. D. (2005). Chronic toxicological evaluation of NovaSil clay in the diet of Sprague-Dawley rats. Toxicologist 84:1402.
Dash, B., Afriyie-Gyawu, E., Huebner, H. J., Wang, J.-S., Jolly, P. E. and Phillips, T. D. (2005). Single nucleotide polymorphism at exon 4 in the microsomal epoxide hydrolase gene is associated with increased aflatoxin albumin adducts in the blood of humans in Ghana. Toxicologist 84:1283.
Tang, L., Cai, Q., Wang, Z., Luo, H., Wang, S., Xie, Y., Yu, J., Wang, K., Hu, X., Huang, T., Su, J., Sun, G., Wang, J.-S. (2005). Validation of Fumonisin Biomarkers for Studying Human Cancer Risks. Proc AACR. 46:4061.
Wang, Z., Tang, Y., Sun, G., Xie, Y., Wang, S., Hu, X., Tang, L. and Wang, J.-S. (2005) Genetic Polymorphisms of CYP2E1 and GSTM1 and T1 on Susceptibility to Esophageal Cancer in Huaian, China. Proc. AACR, 46:4923.
Guan, G., Tang, L., Cai, Q. and Wang, J.-S. (2005). Stability and Uptake of Lycopene in Normal and Tumorigenic Human Prostate Cells. Proc. AACR. 46:6079
He, X-Y., Tang, L., Cai, Q., Wang, J.-S. and Hong, J-Y. (2005). Identification of human CYP2A13 as an efficient enzyme for the metabolic activation of aflatoxin B1. Proc AACR. 46:2086
McKean, C., Tang, L., Billam, M., Luo, H., Tang, M., Thodorakis, C., Kendall, R. and Wang, J.-S. (2004). Combinative toxicity of multiple mycotoxin mixtures in animals and human cells. Toxicologist, 78:1035
Billam, M., Tang, L., Tang, M., Luo, H., McKean, C. and Wang, J.-S. (2004). Combinative toxic effects of aflatoxin B1 and microcystin-LR in the human cell lines and vertebrates. Toxicologist, 78:1030
Tang, L., Guan, H., Luo, H., Tang, M., Billam, M., Ding, X. and Wang, J.-S. (2004). Modulation of aflatoxin biomarkers by natural lycopene in rats. Proc. AACR. 45: 4027.
Luo, H., Tang, L., Tang, M., Billam, M., Huang, T., Yu, J., Wei, Z., Liang, Y., Wang, K., Zhang, Z., Zhang, L., Sun, S., Martin, C. and Wang, J.-S. (2004). Validation of green tea polyphenol biomarkers in high-risk population of liver cancer. AACR. 45: 5498.
Luo, H., Tang, L., Billam, M., Tang, M., Huang, T., Yu, J., Wei, Z., Liang, Y., Wang, K., Zhang, Z., Zhang, L., Sun, S. and Wang, J.-S. (2003). Chemoprevention trial of green tea polyphenols in high-risk population of liver cancer: Modulation of urinary excretion of green tea polyphenols and 8-hydroxydeoxyguanosine. Cancer Epidemiol. Biomarkers & Prev. 12:1349s (C180).
Tang, L., Tang, M., Luo, H., Huang, T., Yu, J., Wei, Z., Liang, Y., Wang, K., Zhang, Z., Zhang, L., Sun, S. and Wang, J.-S. (2003). Chemoprevention trial of green tea polyphenols in high-risk population of liver cancer: Modulation of serum and urinary aflatoxin biomarkers. Cancer Epidemiol. Biomarkers & Prev. 12:1349s (C181).
Tang, L., Jin, T., Zeng, X., Zhou, Y., and Wang, J.-S (2003). Natural lycopene inhibits the growth of prostate cancer by androgen-independent mechanism. Proc. AACR. 44: 883
Wang, J.-S., Huang, T.-R., Yu, J., Wei, Z., Liang, Y., Li, Y., Wang, K., Shi, J., Cui, Y., Luo, H., Tang, L., Liu, H-Q., Billam, M., Zhang, Z.-Q., and Zhang, L. (2003). Chemoprevention trial of green tea polyphenols in high-risk population of liver cancer. Proc. AACR. 44:4801
Wang, J.-S., Wang, S.-K, Su, J.-J, Huang, T.-R., Hu, X., Yu, J-H., Wei, Z., Liang, Y., Liu, Y., Luo, H., Sun, G-J. (2003). Food contamination of fumonisin B1 in high-risk areas of esophageal and liver cancer. Toxicologist, 72:914
Liu, Y., Tang L., Lian, M, Mckean, C., Wu, H., Liu, H.-Q., Theodorakis, C. W., Kendall, R. J., and Wang, J.-S. (2003). Comparative acute and combinative toxicity of aflatoxin B1 and fumonisin B1 in animals and human cells. Toxicologist, 72:913
Lian, M., Yang, X., Su, J-J., Huang, T-R., Wei, Z., Liang, Y., Luo, H., Wang, S-K, Sun, G-J., and Wang, J.-S. (2003). Validation of fumonisin biomarkers in high-risk population of liver cancer. Toxicologist, 72:1173.
Wang, J-S., Liu, Y., Theodorakis, C.W., Chiodo, L., and Kendall, R.J. (2002). Comparative acute and combinative toxicity of aflatoxin B1 and T-2 toxin in rats and fish. Toxicologist, Toxicol Sci. 66S:936
Liu, Y., Wan, S., Yu, S-Z., Lian, M., Jin, Y., Luo, H., Kuang, S-Y., Wu, Y., Song, L-R., Qian, G-S., and Wang, J.-S. (2002). Cocarcinogenicity of aflatoxin B1 and cyanobaterial toxins in hepatitis B virus-X gene transgenic mice. Proc AACR 43:4988
Wang, J-S, He X, and Busby WF, Jr. (2001). Tumorigenicity of airborne complex mixture. Toxicologist, 60:730.
Sun G, Chen J, Qian G-S, Jing X-P, and Wang J-S. (2001). A nutritional epidemiologic study in residents of Qidong with higher and lower incidence of liver cancer. Proc AACR 42, 4090.
Wang, J.-S., Huang, T., Su, J. J., Liang, F., Zhang, L., Zhang, Z., Wei, Z., Liang, Y., Kuang, S.-Y., Qian, G.-S., Sun, G., He, X., Kensler, T. W., and Groopman, J. D. (2000). Etiological risk factors for human hepatocellular carcinoma in Fusui, Guangxi, People’s Republic of China: an update. Proc. AACR 41: 3127
Li, Y., Su, J.-J., Qin, L.-L., Egner, P. A., Wang, J.-S., Groopman, J. D., Kensler, T. W., and Roebuck, B. D. (1999) Modulation of Aflatoxin B1 adducts by oltipraz in the tree shrew. Proc. AACR 40:1732.
Rashid, A, Wang, J.-S, Qian, G.-S, Hamilton S. R. and Groopman, J. D. (1998). Genetic alterations in hepatocellular carcinomas from People’s Republic of China. Proc. AACR 39:3719
Spannhake, E. W., Wang, J.-S., Shen, X., Hecht, S. S., and Groopman, J. D. (1998). Human bronchial epithelial cells metabolism of tobacco-specific nitrosamine 4-(methylnitrosa-mino)1-(3-pyridyl)-1-butanone. To ALA/ATS international Conference April 24-29, 1998, Chicago, IL.
Wang, J.-S., He, X., Hecht, S. S, Groopman, J. D. and Spannhake, E. W. (1997). Metabolism and activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in primary human bronchial epithelial cells and BEAS-2B cells. Proc. AACR 38:2263.
Kensler, T. W., Wang, J.-S., Kuang S.-Y., Qian, G-S., Zhu, Y-R., and Groopman, J. D. (1996).Molecular epidemiology of aflatoxin hepatocarcinogenesis in Qidong, People’s Republic of China. Modulation of Chemical Toxicity and Risk Assessment, June 9-12,1996, Tucson, Arizona.
Kamataki, T., Li, Y., Sasaki, M., Wang, J.-S., Groopman, J. D., and Katsuki, M. (1996). Toxicological evaluation of transgenic mice carrying the CYP3A7, encoding a human fetus-specific P450. 11th international Symposium on microsome and drug oxidation, Los Angeles.
Wang, J.-S., Strickland, P. T., Abubaker, S., He, X. and Groopman, J. D. (1996). Novel aflatoxin-lysine specific monoclonal antibodies for biomarker studies. Toxicologist, 16,1133.
Wang, J.-S., Qian, G.-S., Yu, S.-Z., He, X., Zarba, A., Zhu, Y.-R., Wild, C. P. and Groopman, J. D. (1996). Validation of methods and long-term stability of aflatoxin-albumin adducts in samples from high risk populations for liver cancer Proc. AACR 37:711
Mace, K., Aguillar, F., Vautravers, P., Gonzalez, F., Wang, J.-S., Groopman, J. D., Harris, C. C. and pfeifer, A. M. A. (1996). AFB1 metabolism and p53 mutations in metabolically competent human liver epithelial cell lines. Proc. AACR 37:686.
Wang, J.-S., Qian, G-S., Zhu, Y-R., Zarba, A., Munoz, A., Kensler, T. W. and Groopman, J. D. (1995) Temporal patterns and persistence of aflatoxin-albumin adducts in residents of Daxin Township, Qidong, PRC, Proc. AACR 36:1682
CURRENT FUNDED RESEARCH GRANTS
1 RO1 CA 90997 Wang (PI) 06/16/03 – 05/31/08
NCI/NIH $469,061/first year; $1,834,573/whole project
Chemoprevention of green tea polyphenols on liver cancer
The major goal of this project is to study chemopreventive effect of green tea polyphenols on reducing various carcinogen biomarkers and incidence of primary liver cancer in a 5-year clinical trial in 1,800 high-risk people.
W911SR-04-C0050 Wang (PI) 10/01/2000 – 03/28/2006
RDECOM, US Army $250,000/Current year; $1,826,324/whole project
Combinative Toxicity Studies of Biotoxin Mixtures
The major goal of this research contract is to study acute toxicity of various biotoxin mixtures in rats and fish model and to develop method to detect these biotoxin mixtures in environmental samples and biological fluids.
1 R21 CA94683-03 Wang (PI) 10/01/01 – 8/31/05
NCI $182,500/first year; $547,500/whole project
Validation of Fumonisin and Microcystin Biomarkers
The major goal of this project is to validate fumonisin and microcystin biomarkers in human populations and to apply the validated biomarkers for human cancer risk studies.
USAID S040054 Phillips (PI) 8/01/2004 – 07/31/2007
USAID $200,000 for Wang at TTU
Short-term safety evaluation of NovaSil in humans
The major goal of this study is to evaluate safety of NovaSil in healthy human volunteers.
Small Project 04/01/03 – 03/31/07
University of Alabama $50,000 for Wang at TTU
Analysis of aflatoxin-albumin adducts in Ghanaian human serum samples
The major goal is to analyze aflatoxin adducts in samples collected by Dr. Pauline Jolly’s USAID funding studies in Ghana, Africa.
COMPLETED AND PARTICIPATED RESEARCH GRANTS (in USA only)
Trichothecene Mycotoxin Studies, 1983-1987, United States Army Medical Research and Development Command (Contract No. DAMD17-85-C-5208);
Studies of Fossil Fuel Combustion Products, 1988-1993 NIEHS (Grant No. P01-ES01640);
Mechanisms of Regulation of Actin-based Microfilaments, 1991-1995, NIGMS (Grant No. GM37590);
Neutrophil Studies, 1986-1991, NHLBI (Grant No.HL 33565);
Training Program in Environmental Health Sciences, 1994, NIEHS (Grant No. ES07141);
Molecular Biomarkers For Environmental Carcinogens, 1993-1997; 1997-2002, NIEHS P01 ES06052. Role: Co-investigator
DAAD13-00-C-0056 10/01/2000-09/30/2001
SBCCOM, DOD $499,999
Combinative Toxicity of Biotoxin Mixtures
Role: PI
DAAD13-01-C-0053 10/01/01 – 03/31/03
SBCCOM, DOD $434,564/year
Combinative Toxicity of Biotoxin Mixtures
Role: PI
RO3 ES11442 09/01/02 – 08/31/03
NIEHS $73,000/year; $146,000/whole project
Modulation of Oxidated Damage by Tea Polyphenols
Role: PI
DAAD13-02-C-0070 10/01/02 – 03/31/04
SBCCOM, DOD $642,560
Combinative Toxicity of Biotoxin Mixtures
Role: PI
INTERNATIONAL AND NATIONAL PRESENTATIONS
Validation of Fumonisin Biomarkers for Studying Human Cancer Risks (Invited speaker). Gordon Research Conference: Mycotoxins and Phycotoxins, Colby College, Waterville, ME, June 19-24, 2005
Validation of Fumonisin Biomarkers for Studying Human Cancer Risks. American Association for Cancer Research 96th Annual Meeting in Anaheim, CA, April 16-20, 2005.
Genetic Polymorphisms of CYP2E1 and GSTM1 and T1 on Susceptibility to Esophageal Cancer in Huaian, China. Association for Cancer Research 96th Annual Meeting in Anaheim, CA, April 16-20, 2005.
Stability and Uptake of Lycopene in Normal and Tumorigenic Human Prostate Cells. Association for Cancer Research 96th Annual Meeting in Anaheim, CA, April 16-20, 2005.
Chemoprevention of Green Tea Polyphenols on Liver Cancer. American Society of Preventive Oncology 29th Annual Meeting in San Francisco, CA, March 13-15, 2005
Temporal Patterns of Microcystin-LR Contamination in Lakes of West Texas. Society of Toxicology 44th Annual Meeting in New Orleans, LA, March 6-10, 2005.
Validation of Fumonisin Biomarkers in F344 rats. . Society of Toxicology 44th Annual Meeting in New Orleans, LA, March 6-10, 2005.
Short-term safety evaluation of NovaSil in humans. Society of Toxicology 44th Annual Meeting in New Orleans, LA, March 6-10, 2005.
Aflatoxin exposure, liver cancer, HVB interactions and how these connect to world health. Joint Symposium of NIH, FDA, and USAID in Washington, DC. February 25-26, 2005
Short-term Safety Evaluation of NovoSil in humans. USAID Symposium in Texas A&M University, College Station, TX, December 13-15, 2004
Health and Toxic Effect of Biotoxin Mixtures, The 3rd International Academic Conference on Environmental and Occupational Medicine, Shanghai, November 10-12, 2004.
Validation of Fumonisin and Microcystin Biomarkers for Human Cancer Risk Studies, The 14th Annual International Society of Exposure Analysis Conference, Philadelphia, PA, October 19, 2004
Food Components and Prevention of Liver Cancer, Invited by Intercollegiate Faculty of Toxicology, Texas A&M University, College Station, TX, July 9, 2004
Validation of green tea polyphenol biomarkers in high-risk population of liver cancer. American Association for Cancer Research 95th Annual Meeting in Orlando, FL, March 27-31, 2004.
Modulation of aflatoxin biomarkers by natural lycopene in rats. American Association for Cancer Research 95th Annual Meeting in Orlando, FL, March 27-31, 2004.
Combinative toxic effects of aflatoxin B1 and microcystin-LR in the human cell lines and vertebrates. Society of Toxicology 43nd Annual Meeting in Baltimore, MD, March 21-25, 2004.
Combinative toxicity of multiple mycotoxin mixtures in animals and human cells. Society of Toxicology 43nd Annual Meeting in Baltimore, MD, March 21-25, 2004.
Progress in Cancer Prevention, Invited by Guangxi Medical University, Nanning, Guangxi, PR China, November 10-21, 2003.
Chemoprevention trial of green tea polyphenols in high-risk population of liver cancer: Modulation of urinary excretion of green tea polyphenols and 8-hydroxydeoxyguanosine. Second Annual AACR International Conference: Frontiers in Cancer Prevention Research, in Phoenix, AZ, October 26-30, 2003.
Chemoprevention trial of green tea polyphenols in high-risk population of liver cancer: Modulation of serum and urinary aflatoxin biomarkers. Second Annual AACR International Conference: Frontiers in Cancer Prevention Research, in Phoenix, AZ, October 26-30, 2003.
Combinative toxicity of biotoxins and biomarker studies. Gordon Research Conference on Mycotoxins and Phytotoxins in Colby College, Waterville, ME, June 15-20, 2003
Combinative toxicity of biotoxin mixtures. Annual Consortium of Biological Defense Research Meeting in Lubbock, TX, April 28-30, 2003.
Natural lycopene inhibits the growth of prostate cancer by androgen-independent mechanism. American Association for Cancer Research 94th Annual Meeting in Toronto, Canada, April 5-9, 2003.
Chemoprevention trial of green tea polyphenols in high-risk population of liver cancer. American Association for Cancer Research 94th Annual Meeting in Toronto, Canada, April 5-9, 2003.
Food contamination of fumonisin B1 in high-risk areas of esophageal and liver cancer. Society of Toxicology 42nd Annual Meeting in Salt Lake City, UT, March 9-13, 2003.
Comparative acute and combinative toxicity of aflatoxin B1 and fumonisin B1 in animals and human cells. Society of Toxicology 42nd Annual Meeting in Salt Lake City, UT, March 9-13, 2003.
Validation of fumonisin biomarkers in high-risk population of liver cancer. Society of Toxicology 42nd Annual Meeting in Salt Lake City, UT, March 9-13, 2003.
Advances in Liver Cancer Chemoprevention, Invited by the Guangxi Medical University, June 3, 2002.
Biotxins, Bioterrorism, and Health Effect, Invited by the Southeast University, Seminars for Centennial Anniversary of the University, May 8, 2002.
Cocarcinogenicity of aflatoxin B1 and cyanobaterial toxins in hepatitis B virus-X gene transgenic mice. American Association for Cancer Research 93rd Annual Meeting in San Francisco, April 6-10, 2002
Comparative acute and combinative toxicity of aflatoxin B1 and T-2 toxin in rats and fish. Society of Toxicology 41st Annual Meeting in Nashville, TN, March 17-21, 2002
Cancer Chemoprevention of Green Tea Polyphenols, invited by Southeast University, Nanjing, Jiangsu, PR China, December 2001
Food Components and Cancer Chemoprevention, invited by Southern Yangtze Univerity,
Wuxi, Jiangsu, PR.China, December 2001
Molecular Biomarkers for Liver Cancer Studies, invited by Texas AM University, College Station, Texas, October 2001.
Development and Application of Immunoaffinity Method for Biotoxin Studies, invited by International Conference of Biotoxins and Health, August 2001, Beijing, PR China
Biomarkers for Liver Cancer Studies, invited by Fudan University, Shanghai, PR China, May 2001.
Perspectives in Liver Cancer Research, invited by Gunagxi Cancer Institute, Nanning, Guangxi, PR China, May 2001.
Development and application of molecular biomarkers for liver cancer studies, invited by Texas Tech University, Lubbock, Texas, December 1999.
Toxicology: Retrospective and Perspective in the Cross of the Centuries, invited by Nanjing Railway Medical College, Nanjing, P.R. China, October, 1998.
Advances of research in heterocyclic aromatic amines, invited by Shanghai Cancer Institute, Shanghai, PRC, April 1995.
Advances of research in heterocyclic aromatic amines, invited by Nanjing Railway Medical College, Nanjing, PRC, April 1995.
Organ specificity and persistence of DNA adduct formation during tumorigenesis of preweanling mice treated with fluoranthene, invited by Graduate School of Public Health, University of Pittsburgh, PA, November 1993.
Detoxification of Fusarium Toxins, invited by Animal Research Center, Department of Agriculture, Canada, Ottawa, September 1989.
Gordon Research Conference on Mycotoxins and Phytotoxins, July, 1989, Plymouth, New Hampshire. Invited speaker on mycotoxin research in China.
FASEB summer conferences on trichothecene mycotoxins, July, 1986, July 1988, Colorado Springs. Post presentation on oral and skin studies of diacetoxyscirpenol (anguidine) in rats and mice.
TEACHING & TRAINING
Visiting Scientists:
Xiaoling Ding, Professor of Food Sciences, Southern Yantze University, Summer 2002
Wenying Guo, Professor of Food Sciences, Southern Yantze University, Summer 2002
Geng-Sun Qian, Professor of Shanghai Cancer Institute, Summer 2003
Meng Tang, Associate Professor of Southeast University, March 2003- June 2004
Shuang-Yuang Kuang, Research Scientist of Johns Hopkins University, August 2004
Jianjia Su, Professor of Guangxi Cancer Institute, June-August 2005
Jiahua Yu, Associate Professor, Guangxi Cancer Institute, June 2005-
Postdoctoral Trainee in Current Laboratory
Heng-Qian Liu, PhD from Hong Kong University, November 2001-August 2003
Lili Tang, PhD from Fudan University, April 2002- October 2004
Haitao Luo, PhD from Texas Tech University, September 2005-
Graduate Advisees:
Student Graduated:
Qun Sun, Master of Medicine, 1985, NRMC, China
Fuxian Zhao, M.B. in Preventive Medicine, 1983, NRMC, China
Wui Sui, M.B. in Preventive Medicine, 1983, NRMC, China
Yi Li, M.B. in Preventive Medicine, 1983, NRMC, China
Rensheng Zhu, M.B. in Preventive Medicine, 1983, NRMC, China
Jing Tao, M.B. in Preventive Medicine, 1983, NRMC, China
Lian Kung, M.B. in Preventive Medicine, 1983, NRMC, China
Hongbing Zhang, M.B. in Preventive Medicine, 1985, NRMC, China
Yang Chen, M.B. in Preventive Medicine, 1985, NRMC, China
Qun Zhu, M.B. in Preventive Medicine, 1985, NRMC, China
Guiju Sun, PhD, 2001, SMU, China
Christopher McKean, MS, 2004, ENTX, TTU
Yin Xie, MM, 2005, SEU, China
Haitao Luo, PhD, 2005, ENTX, TTU
Students Under Advise:
Li Xu, PhD student, fall 2005- ENTX, TTU
Yuntian Tang, PhD student, fall 2004- ENTX, TTU
Piwen Wang, PhD student, fall 2004- ENTX, TTU
Zeimin Wang, PhD student, fall 2003-, ENTX, TTU
Hongxia Guan, MS student, fall 2003-, ENTX, TTU
Madhavi Billam, PhD student, fall 2002- ENTX, TTU
Qingsong Cai, PhD student, fall 2002-, ENTX, TTU
Fujun Liu, PhD student , Spring 2002- ENTX, TTU
Principal Course Lecturer:
Prior to TTU:
Basic Nutrition and Food Safety, Medical School Class 1982, 1983, and 1984 (150 Medical students each class), Nanjing Railway Medical College
Food Hygiene and Food Toxicology, Preventive Medicine Class 1982, 1983, 1984, and 1985 (50 students in each class), Nanjing Railway Medical College
Methods in Toxicology, Preventive Medicine Class 1983, 1984, and 1985 (50 students in each class), Nanjing Railway Medical College
In TTU:
ENTX 6326 Principles of Toxicology II, Spring 2002, 2004, 2005, 2006
ENTX 6327 Molecular Toxicology, Spring 2001, Fall 2004
ENTX 6300 Molecular & Genetic Toxicology, Fall 2001, 2002, 2003, 2004
ENTX6332 Toxic Effect and Detection Methods of Biotoxins, Fall 2005
ENTX 6366 Advanced Environmental Toxicology, Fall 2001, 2002, 2003
ENTX 7000 Research, 2000-
ENTX 8000 Doctoral Dissertation, 2000-
Participation of Course Teaching in TTU:
TOX 6105 Introductory Seminar, Fall 2000-
TOX 6115 Environmental Toxicology Seminar, Fall 2000-
ENTX 6325 Principles of Toxicology I, Fall 2005
ENTX 6431 Biomarkers in Toxicology, Spring 2005
SERVICES:
Curriculum Committee, TIEHH and Department of Environmental Toxicology, TTU (2000-)
Animal Use and Care Committee, TIEHH and Department of Environmental Toxicology, TTU (2000-)
Graduate Admission Committee, Department of Environmental Toxicology, TTU (2000-2005 and current chair)
Graduate Faculty Review Committee, Department of Environmental Toxicology, TTU (2006-)
Division Leader, Division of Human Health Sciences, TIEHH, TTU (2006-)