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WELCOME! |
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I am an assistant professor in the Department of Environmental Toxicology at The Institute of Environmental and Human Health. I received a Ph.D. in Environmental Toxicology in 2000 from Texas Tech University. My Ph.D. research focused on the identification and characterization of novel cytochrome P450 1 genes in marine vertebrates (fish and cetaceans) and was conducted at the Woods Hole Oceanographic Institution (WHOI) from 1995 until 2000. I pursued research in biomarkers of exposure and effects in marine mammals at WHOI as a post-doctoral investigator from 2001 until 2004. I then moved to the University of Southern Maine for a senior post-doctoral fellowship position where I studied the cytotoxicity and genotoxicity of polycyclic aromatic hydrocarbons in the endangered North Atlantic Right whale and participated in the creation of marine mammal cell lines. During my post-doctoral appointments and from 2000 to 2005, I served as Chief Scientist for the toxicology program of a worldwide sperm whale research cruise sponsored by Ocean Alliance. My involvement in this program was featured in the news section of Science (2004, 2005) and on the Discovery Channel-Canada (2004). My laboratory has recently been featured on NPR "living on earth", in the New York Times and in several other news outlets (2010), see the section "lab photos and news" below for direct links.
July 2010, Lunch outing for the lab From left to right: Sandy Wiggins (Masters student), Jennifer Cole (Doctoral student), Dr. Celine Godard-Codding, Greg Zychowski (Masters student), Javi Arzate (NIH Undergraduate student)
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EDUCATION: |
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Ph.D., Environmental Toxicology, Texas Tech University, Lubbock, TX. 2000. Dissertation: Novel Cytochrome P450 1 genes in marine vertebrates: characterization and expression of multiple CYP1B genes in the fish Stenotomus chrysops and of CYP1A1 and CYP1B1 in the cetacean Stenella coeruleoalba. Research conducted at the Woods Hole Oceanographic Institution.
M.S., Microbiology, Clemson University,
Clemson, SC. 1994
Diplôme d’Ingénieur de l’Ecole
Nationale d’Ingénieurs des Techniques Agricoles de Dijon (E.N.I.T.A de
Dijon), France. Joint degree with Clemson University.
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RESEARCH INTERESTS: |
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My research interests focus on genomic and cellular toxicology, mechanistic toxicology, endangered wildlife ecotoxicology and conservation, biomarkers, robustness and resilience to stress in marine organisms. Species of special interest are marine mammals and sea turtles. I am specifically interested in creating and using sea turtle cell lines to determine the sensitivity of these species to marine pollutants and in cloning and expressing key dolphin metabolizing enzymes in order to assess their ability to process chemicals. I am also interested in investigating pollutant sensitivity and metabolism in these taxa using organotypic culture, genomics and proteomics techniques. Although this is by no means a comprehensive list, some specific topics of interest are: |
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SELECTED PUBLICATIONS: |
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Godard-Codding CAJ, Clark R,
Fossi MC, Marsili L, Maltese S, West AG, Valenzuela L, Rowntree V,
Ildiko Polyak, Cannon JC, Pinkerton K, Rubio-Cisneros N, Mesnick S,
Cox SB, Kerr I, Payne R, and Stegeman JJ. Pacific Ocean–wide
Profile of CYP1A1 Expression, Stable Carbon and Nitrogen Isotope Ratios,
and Organic Contaminant Burden in Sperm Whale Skin Biopsies.
Environmental Health Perspectives 119 (3): 337-343. Depledge MH, Godard-Codding CAJ, Bowen RE.2010. Light pollution in the sea. Marine Pollution Bulletin, 60:1383-1385. Book Chapter: Smith PN, Afzal M, Al-Hasan R, Bouwman H, Castillo LE, Depledge MH, Subramanian M, Dhananjayan V, Fossi C, Kitulagodage M, Kylin H, Law R, Marsili L, O’Hara T, Spinola M, Story P, Godard-Codding, CAJ. 2010. “Global Perspectives on Wildlife Toxicology: Emerging Issues” in Kendall, Ronald J., Cobb, George P., Cox, Stephen, Lacher, Thomas, eds. Wildlife Toxicology: Emerging Contaminant and Biodiversity Issues, Taylor and Francis Group. Brausch JM, Blackwell BR, Beall BN, Caudillo C, Venkata K, Godard-Codding CAJ, Cox SB., Cobb G, Smith PN. 2010. Effects of polycyclic aromatic hydrocarbons in Northern bobwhite quail (Colinus virginianus). Journal of Toxicology and Environmental Health, Part A, 73, 540-551. Smith PN, Cobb G, Godard-Codding CAJ, Hoff D, McMurry ST, Rainwater TR, Reynolds KD. 2007. Invited review. Contaminant exposure in terrestrial vertebrates. Environmental Pollution, 150, 41-64 Rubio-Cisneros N, Mesnick S, Vazquez-Juarez R, Urban Ramirez J, Godard CAJ, Payne R and A Dizon. 2006. Genetic sex determination supports the Gulf of California as an important habitat for sperm whales (Physeter macrocephalus). Latin American Journal of Aquatic Mammals 5(2), 125-128.
Godard CAJ, Wise SS, Kelly,
RS, Goodale, B, Kraus S, Romano T, O’Hara T and JP Wise Sr. 2006.
Benzo Godard CAJ, Goldstone JV, Said MS, Dickerson RL, Woodin BR and JJ Stegeman. 2005. The new vertebrate CYP1C family: Cloning of new subfamily members and phylogenetic analysis. Biochemical and Biophysical Research Communications 331, 1016-1024. Godard CAJ, Smolowitz RM, Wilson JY, Payne RS, and JJ Stegeman. 2004. Induction of cetacean cytochrome P4501A1 by β-naphthoflavone exposure of skin biopsy slices. Toxicological Sciences, 80, 268-275. Godard CAJ, Leaver MJ, Said M, Dickerson RL, George S and JJ Stegeman. 2000. Identification of cytochrome P450 1B-like sequences in two teleost fish species (scup, Stenotomus chrysops and plaice, Pleuronectes platessa) and in a cetacean (striped dolphin, Stenella coeruleoalba). Marine Environmental Research 50, 7-10. Peden-Adams M, Alonso K, Godard C, Skipper S, Mashburn W, Hoover J, Charbonneau C, Henshel D, and R Dickerson. 1998. Effects of environmentally relevant concentrations of 2,3,7,8-TCDD on domestic chicken immune function and CYP450 activity: F1 generation and egg injection studies. Chemosphere 37 (9-12):1923-1939. |
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TIEHH |