Dr. Lenka Halámková

Assistant Professor, High-Dimensional Data Analysis

 

Research Scientist, University at Albany, SUNY, Albany, NY, 2013-2020

Research Assistant Professor, Department of Chemistry & Biomolecular Science, Clarkson University, Potsdam, NY, 2012-2013

Research Associate, Department of Biology, Clarkson University, Potsdam, NY, 2009-2013

Ph.D. Interdisciplinary Study of Quaternary, Masaryk University, Brno, Czech Rep., 2006

Research Associate, Academy of Sciences, Brno, Czech Rep., 2002-2004

M.S. Systematic Zoology and Ecology, Masaryk University, Brno, Czech Rep., 2000

B.S. Systematic Biology and Ecology, Masaryk University, Brno, Czech Rep., 1997

 

Research Interests:

High-dimensional data analysis

Machine learning

Multivariate analysis

Statistical methods for analyzing biological data

Evolutionary biology

 

Classes:

FSCI-5353-001 Research Methods in Forensic Science

ENTX-6351-001 Analytical Toxicology Lecture

 

Bio:

Her recent work is focused on the development and application multivariate statistical methods on Raman spectroscopic data for forensic purposes. She contributed to a development of novel methods for the detection and classification of biological stains, gunshot residue, other trace evidence found at a crime scene and their importance for profiling a person based on body fluids.

Additionally, in the field of biochemical computing based on enzymatic reaction systems, Dr. Halámková works on the biorecognition of different characteristics, such as, ethnicity and gender of forensic subjects using biocatalysis and enzymatic -based sensors. These approaches are based on analysis of biological marker patterns and their significance to the particular personal attribute of a personal forensic marker. She performs for the project basic data analysis, statistical tests, regression and prediction analysis.

In the field of evolutionary biology, Dr. Halámková focuses on gathering information on origins, anatomy, development of species.  She is in interested in the dynamics of the origin and development of vertebrates, especially amphibians and reptiles.

 

Recent Publications (last 7 years):

  1. Roček Z., Halámková L., Muzzopappa P. Developmental dynamics of two closely related species of Bombina (Amphibia: Anura) in context of their fossil evidence. (submitted)

  2. Vyas B., Halámková L., Lednev I. K. A universal test for the forensic identification of all main body fluids including urine, Forensic Chemistry, 2020; 20, 100247, doi.org/10.1016/j.forc.2020.100247.

  3. Casey T., Mistek E., Halámková L., Lednev I. K. Raman spectroscopy for forensic semen identification: Method validation vs. environmental interferences, Vibrational Spectroscopy, 2020; Volume 109,103065; doi.org/10.1016/j.vibspec.2020.103065.

  4. Al‐Hetlani E., Halámková L., Amin M.O., Lednev I.K. Differentiating smokers and nonsmokers based on Raman spectroscopy of oral fluid and advanced statistics for forensic applications, Journal of Biophotonics, 2019; 13(3); doi.org/10.1002/jbio.201960123.

  5. Hair M.E., Gerkman R., Mathis A.I., Halámková L., Halámek J. Noninvasive Concept for Optical Ethanol Sensing on the Skin Surface with Camera-Based Quantification, Analytical Chemistry, 2019; 91 (24), 15860; doi: 10.1021/acs.analchem.9b04297.

  6. Rosenblatt R., Halámková L., Doty K.C., de Oliveira Jr. E.A.C., Lednev I.K. Raman spectroscopy for forensic bloodstain identification: Method validation vs. environmental interferences, Forensic Chemistry, 2019; Volume 16, 100175; doi: 10.1016/j.forc.2019.100175.

  7. Mistek E., Halámková L., Lednev I.K. Phenotype profiling for forensic purposes: Nondestructive potentially on scene attenuated total reflection Fourier transform-infrared (ATR FT-IR) spectroscopy of bloodstains, Forensic Chemistry, 2019; Volume 16, 100176; doi.org/10.1016/j.forc.2019.100176.

  8. Ralbovsky N.M., Halámková L., Wall K., Anderson-Hanley C., Lednev I.K. Screening for Alzheimer’s Disease Using Saliva: A New Approach Based on Machine Learning and Raman Hyperspectroscopy, Journal of Alzheimer's Disease, 2019; 71(4), 1351-1359;  DOI: 10.3233/JAD-190675

  9. Ryzhikova E., Ralbovsky N.M., Halámková L., Celmins D., Malone P., Molho E., Quinn J., Zimmerman E.A., Lednev I.K. Multivariate Statistical Analysis of Surface Enhanced Raman Spectra of Human Serum for Alzheimer’s Disease Diagnosis, Appl. Sci., 2019; 9(16), 3256; DOI.org/10.3390/app9163256.

  10. Takamura A., Halámková L., Ozawa T., Lednev I.K. Phenotype Profiling for Forensic Purposes: Determining Donor Sex Based on Fourier Transform Infrared Spectroscopy of Urine Traces, Analytical Chemistry, 2019; 91 (9), 6288, DOI: 10.1021/acs.analchem.9b01058.

  11. Bueno J., Halámková L., Rzhevskii A., Lednev I.K. Raman microspectroscopic mapping as a tool for detection of gunshot residue on adhesive tape, Analytical and bioanalytical chemistry, 2018; 410 (28), 7295; doi.org/10.1007/s00216-018-1359-1.

  12. Fikiet M.A., Khandasammy S.R. , Mistek E., Ahmed Y., Halámková L., Bueno J., Lednev I. K. Surface enhanced Raman spectroscopy: A review of recent applications in forensic science, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018; 197, 255; doi: 10.1016/j.saa.2018.02.046

  13. Khandasammy S.R., Fikiet M.A., Mistek E., Ahmed Y., Halámková L., Bueno J., Lednev I.K. Bloodstains, paintings, and drugs: Raman spectroscopy applications in forensic science, Forensic Chemistry, 2018; 8, 111; doi: 10.1016/j.forc.2018.02.002

  14. Hair M.E., Mathis A.I., Brunelle E.K., Halámková L., Halámek J. Metabolite Biometrics for the Differentiation of Individuals, Analytical chemistry, 2018; 90 (8), 5322; doi: 10.1021/acs.analchem.8b00414

  15. Brunelle E., Huynh C., Alin E., Eldridge M., Le A.M., Halámková L., Halámek J. Fingerprint Analysis: Moving Toward Multiattribute Determination via Individual Markers, Analytical chemistry, 2017; 90 (1), 980; doi.org/10.1021/acs.analchem.7b04206.

  16. Brunelle E., Le A.M., Huynh C., Wingfield K., Halámková L., Agudelo J., Halámek J. Coomassie brilliant blue g-250 dye: an application for forensic fingerprint analysis, Analytical chemistry, 2017; 89 (7), 4314; doi.org/10.1021/acs.analchem.7b00510.

  17. Katz E., Wang J., Halámek J., Halámková L. Enzyme Logic Systems: Biomedical and Forensic Biosensor Applications. In: Label-Free Biosensing, M. Schöning, A. Poghossian (Eds.), Springer Series on Chemical Sensors and Biosensors, 2017: pp. 345-381.

  18. Mistek E., Halámková L., Doty K.C., Muro C.K., Lednev I.K. Race differentiation by Raman spectroscopy of a bloodstain for forensic purposes, Analytical chemistry, 2016; 88 (15), 7453; doi.org/10.1021/acs.analchem.6b01173.

  19. Katz E., Halámek J., Halámková L., Bakshi S., Agudelo J., Huynh C. Biochemical analysis of biomarkers for forensic applications. Chapter 8 in Forensic Science: A Multidisciplinary Approach, E. Katz (Ed.), Wiley-VCH, Weinheim, Germany, 2016: pp. 151-176.

  20. Muro C.K., Doty K.C., Bueno J., Halámková L., Lednev I.K. Vibrational Spectroscopy for Forensic Applications. Chapter 2 in Forensic Science: Chemistry, Physics, Biology and Engineering for Justice. Ed. E. Katz and J. Halámek. Wiley-VCH , Weinheim, Germany, 2016: pp. 5-54.

  21. Agudelo J., Halámková L., Brunelle E., Rodrigues R., Huynh C., Halámek J. Ages at a crime scene: Simultaneous estimation of the time since deposition and age of its originator, Analytical chemistry, 2016; 88 (12), 6479; doi.org/10.1021/acs.analchem.6b01169.

  22. Brunelle E., Huynh C., Le A.M., Halámková L., Agudelo J., Halámek J. New horizons for ninhydrin: Colorimetric determination of gender from fingerprints, Analytical chemistry, 2016; 88 (4), 2413; doi.org/10.1021/acs.analchem.5b04473.

  23. Doty K.C., Muro C.K., Bueno J., Halámková L., Lednev I.K. What can Raman spectroscopy do for criminalistics?, Journal of Raman Spectroscopy, 2016; 47 (1), 39; doi.org/10.1002/jrs.4826.

  24. Huynh C., Brunelle E., Halámková L., Agudelo J., Halámek J. Forensic identification of gender from fingerprints, Analytical chemistry, 2015; 87 (22), 11531; doi.org/10.1021/acs.analchem.5b03323.

  25. Muro C.K., Doty K.C., Bueno J., Halámková L., Lednev I.K. Vibrational Spectroscopy: Recent Developments to Revolutionize Forensic Science, Analytical Chemistry, 2015; 87 (1), 306; doi: 10.1021/ac504068a.

  26. Ryzhikova E., Kazakov O., Halámková L., Celmins D., Malone P., Molho E., Zimmerman E. A., Lednev I. K., Raman spectroscopy of blood serum for Alzheimer’s disease diagnostics: specificity relative to other types of dementia, J. Biophotonics, 2015, 8(7), 584; doi: 10.1002/jbio.201400060.

  27. Bakshi S., Halámek J., Halámková L., Katz E., Biocatalytic analysis of biomarkers for forensic identification of gender, Analyst, 2014; 139(3), 559; doi: 10.1039/c3an02055j.

  28. Halámková L., Schulte J. A., Langen T. A., Patterns of sexual size dimorphism in Chelonia, Biological Journal of the Linnean Society, 2013; 108(2), 396; doi.org/10.1111/j.1095-8312.2012.02015.x.

  29. Kramer F., Halámková L., Poghossian A., Schöning M.J., Katz E., Halámek J., Biocatalytic analysis of biomarkers for forensic identification of ethnicity between Caucasian and African American groups. Analyst, 2013; 138(21), 6251; doi: 10.1039/c3an01062g.

  30. Privman V., Zavalov O., Halámková L., Moseley F., Halámek J., Katz E. Networked Enzymatic Logic Gates with Filtering: New Theoretical Modeling Expressions and Their Experimental Application, The Journal of Physical Chemistry B, 2013; 117(48), 14928; doi: 10.1021/jp408973g.

  31. Mailloux S., Halámek J., Halámková L., Tokarev A., Minko S., Katz E. Biomolecular release triggered by glucose input - bioelectronic coupling of sensing and actuating systems, Chemical Communications, 2013; 49(42): 4755; doi: 10.1039/c3cc42027b.

  32. Castorena-Gonzalez J.A., Foote C., MacVittie K., Halámek J., Halámková L., Martinez-Lemus L.A., Katz E. Biofuel Cell Operating in Vivo in Rat, Electroanalysis, 2013; 25(7): 1579; doi.org/10.1002/elan.201300136.

  33. MacVittie K., Halámek J., Halámková L., Southcott M., Jemison W. D., Lobel R., Katz E. From "cyborg" lobsters to a pacemaker powered by implantable biofuel cells, Energy & Environmental Science, 2013; 6(1), 81; doi.org/10.1039/C2EE23209J.

  34. Southcott M., MacVittie K., Halámek J., Halámková L., Jemison W. D., Lobel R., Katz E. A pacemaker powered by an implantable biofuel cell operating under conditions mimicking the human blood circulatory system - battery not included, Physical Chemistry Chemical Physics, 2013; 15(17), 6278; doi: 10.1039/c3cp50929j.

 

 

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The Department of Environmental Toxicology (ENTX) is the academic home for the core faculty of The Institute of Environmental and Human Health (TIEHH) and the Institute for Forensic Science (IFS) at Texas Tech University. TIEHH and IFS provide faculty and graduate students opportunities for multidisciplinary research and scholarly engagement related to environmental, forensic and human health sciences.

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