Associate Professor, Environmental, Clinical & Analytical Chemistry


Adjunct Professor, Hawaii Institute of Marine Biology University of

Hawaii, Manoa


Ph.D. Organic Chemistry, University of Hawai’i

M.A.T. Teaching Chemistry, Texas Christian University

B.S. Chemistry, University of Texas at San Antonio


Research Interests:

Environmental Chemistry and Toxicology

Clinical Chemistry

Natural Products Chemistry



ENTX 6115 001, Advanced Topics in LC-MS

ENTX 6351, Analytical Toxicology

ENTX 6445, Chemical Sources and Fates in Environmental Systems




Prof. Klein is a chemist with experience in natural products, environmental and clinical chemistry. He joined the faculty at TIEHH in 2012 after working with environmental chemistry laboratories in Texas and Hawai’i. He comes to TIEHH from heading the Chemical Terrorism Response Lab (part of the Centers for Disease Control Laboratory Response Network) in Texas. Prof. Klein has a wide range of research interests.


     1. Detection and quantitation of metals and metalloids by ICP-MS

     2. Isolation, purification, detection and quantitation of organic compounds by GC-MS and LC-MSn

     3. Purification and identification of biologically active natural products

     4. Identification of chemical communication compounds from marine organisms with HIMB

     5. Identification of toxic compounds

     6. Identification and quantitation of compounds in wastewater and drinking water

     7. Endocrine disrupting compounds


Research in his lab is focused on three major instrument platforms; inductively coupled plasma-mass spectrometry, gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry.  Students work in a supportive environment to learn the principles of analytical chemistry as applied to a wide variety of problems as suits their interests.


• Presentation at the Centers for Disease Control National Laboratory Response Network Meeting,

    The Use of Stable Primary Standards for LC-MS

• Current submission to American Society of Mass Spectrometry National Meeting:

    Detection of Metabolites and Drugs in the Wastewater of Lubbock, TX

    David Klein, Ph.D.; Brett Blackwell; Todd Anderson, Ph.D.;  Gaurav Pandey, M.S.; Kathy Sperry, Ph.D.

• Current submission to Society for Environmental Toxicology and Chemistry (SETAC),

    Determination of Chemical Contaminants from Military Bombing Ranges Near the Ocean in Hawaii


​Hawaii Institute of Marine Biology  (HIMB)

Bellows Beach, Oahu

Indooor Radon

figure showing the decay chain for radon

The Department of Environmental Toxicology (ENTX) is the academic home for the core faculty of The Institute of Environmental and Human Health (TIEHH) and the Institute for Forensic Science (IFS) at Texas Tech University. TIEHH and IFS provide faculty and graduate students opportunities for multidisciplinary research and scholarly engagement related to environmental, forensic and human health sciences.


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